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D80 Immunodeficiency with predominantly antibody defects

ICD-10-CM category D80 sits in Chapter 3 (Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, D50-D89). It contains 10 billable codes for FY2027, effective October 1, 2026 to September 30, 2027. Always code to the most specific code available: a code with more characters that describes the diagnosis more precisely takes priority over a shorter one.

Billable codes in D80

CodeDescription
D80.0Hereditary hypogammaglobulinemia
D80.1Nonfamilial hypogammaglobulinemia
D80.2Selective deficiency of immunoglobulin A [IgA]
D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
D80.4Selective deficiency of immunoglobulin M [IgM]
D80.5Immunodeficiency with increased immunoglobulin M [IgM]
D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
D80.7Transient hypogammaglobulinemia of infancy
D80.8Other immunodeficiencies with predominantly antibody defects
D80.9Immunodeficiency with predominantly antibody defects, unspecified

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