D57 Sickle-cell disorders
ICD-10-CM category D57 sits in Chapter 3 (Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, D50-D89). It contains 43 billable codes for FY2027, effective October 1, 2026 to September 30, 2027. Always code to the most specific code available: a code with more characters that describes the diagnosis more precisely takes priority over a shorter one.
Subcategories
D57.0 Hb-SS disease with crisisD57.2 Sickle-cell/Hb-C diseaseD57.21 Sickle-cell/Hb-C disease with crisisD57.4 Sickle-cell thalassemiaD57.41 Sickle-cell thalassemia, unspecified, with crisisD57.43 Sickle-cell thalassemia beta zero with crisisD57.45 Sickle-cell thalassemia beta plus with crisisD57.8 Other sickle-cell disordersD57.81 Other sickle-cell disorders with crisis
Billable codes in D57
| Code | Description |
|---|---|
D57.00 | Hb-SS disease with crisis, unspecified |
D57.01 | Hb-SS disease with acute chest syndrome |
D57.02 | Hb-SS disease with splenic sequestration |
D57.03 | Hb-SS disease with cerebral vascular involvement |
D57.04 | Hb-SS disease with dactylitis |
D57.09 | Hb-SS disease with crisis with other specified complication |
D57.1 | Sickle-cell disease without crisis |
D57.20 | Sickle-cell/Hb-C disease without crisis |
D57.211 | Sickle-cell/Hb-C disease with acute chest syndrome |
D57.212 | Sickle-cell/Hb-C disease with splenic sequestration |
D57.213 | Sickle-cell/Hb-C disease with cerebral vascular involvement |
D57.214 | Sickle-cell/Hb-C disease with dactylitis |
D57.218 | Sickle-cell/Hb-C disease with crisis with other specified complication |
D57.219 | Sickle-cell/Hb-C disease with crisis, unspecified |
D57.3 | Sickle-cell trait |
D57.40 | Sickle-cell thalassemia without crisis |
D57.411 | Sickle-cell thalassemia, unspecified, with acute chest syndrome |
D57.412 | Sickle-cell thalassemia, unspecified, with splenic sequestration |
D57.413 | Sickle-cell thalassemia, unspecified, with cerebral vascular involvement |
D57.414 | Sickle-cell thalassemia, unspecified, with dactylitis |
D57.418 | Sickle-cell thalassemia, unspecified, with crisis with other specified complication |
D57.419 | Sickle-cell thalassemia, unspecified, with crisis |
D57.42 | Sickle-cell thalassemia beta zero without crisis |
D57.431 | Sickle-cell thalassemia beta zero with acute chest syndrome |
D57.432 | Sickle-cell thalassemia beta zero with splenic sequestration |
D57.433 | Sickle-cell thalassemia beta zero with cerebral vascular involvement |
D57.434 | Sickle-cell thalassemia beta zero with dactylitis |
D57.438 | Sickle-cell thalassemia beta zero with crisis with other specified complication |
D57.439 | Sickle-cell thalassemia beta zero with crisis, unspecified |
D57.44 | Sickle-cell thalassemia beta plus without crisis |
D57.451 | Sickle-cell thalassemia beta plus with acute chest syndrome |
D57.452 | Sickle-cell thalassemia beta plus with splenic sequestration |
D57.453 | Sickle-cell thalassemia beta plus with cerebral vascular involvement |
D57.454 | Sickle-cell thalassemia beta plus with dactylitis |
D57.458 | Sickle-cell thalassemia beta plus with crisis with other specified complication |
D57.459 | Sickle-cell thalassemia beta plus with crisis, unspecified |
D57.80 | Other sickle-cell disorders without crisis |
D57.811 | Other sickle-cell disorders with acute chest syndrome |
D57.812 | Other sickle-cell disorders with splenic sequestration |
D57.813 | Other sickle-cell disorders with cerebral vascular involvement |
D57.814 | Other sickle-cell disorders with dactylitis |
D57.818 | Other sickle-cell disorders with crisis with other specified complication |
D57.819 | Other sickle-cell disorders with crisis, unspecified |
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